COMPLETE NUCLEOTIDE-SEQUENCE OF AN INFLUENZA-VIRUS HEMAGGLUTININ GENE FROM CLONED DNA

被引：256

作者：

PORTER, AG

BARBER, C

CAREY, NH

HALLEWELL, RA

THRELFALL, G

EMTAGE, JS

机构：

[1] Searle Research Laboratories, High Wycombe, Bucks, Lane End Road

来源：

NATURE | 1979年 / 282卷 / 5738期

关键词：

D O I：

10.1038/282471a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A synthetic fowl plague virus (FPV) haemagglutinin gene has been cloned in bacteria and the complete sequence of the RNA gene deduced. It is 1,742 nucleotides long and the mRNA codes for 563 amino acids in an uninterrupted sequence. The nature of some of the important domains in the haemagglutinin has been established, and their structure is discussed in relation to their function. Extensive amino acid sequence homologies exist between FPV and human influenza haemagglutinins. © 1979 Nature Publishing Group.

引用

页码：471 / 477

页数：7

共 54 条

[1] NUCLEOTIDE-SEQUENCE CODING FOR THE SIGNAL PEPTIDE AND N-TERMINUS OF THE HEMAGGLUTININ FROM AN ASIAN (H2N2) STRAIN OF INFLUENZA-VIRUS [J].