RELIABILITY OF THE PORPHOBILINOGEN SCREENING ASSAY

被引：10

作者：

BUTTERY, JE

CARRERA, AM

PANNALL, PR

机构：

[1] Department of Clinical Chemistry, The Queen Elizabeth Hospital, SA

来源：

PATHOLOGY | 1990年 / 22卷 / 04期

关键词：

URINE PBG; SCREENING METHOD; WATSON-SCHWARTZ; ANALYTICAL SENSITIVITY AND SPECIFICITY;

D O I：

10.3109/00313029009086660

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

A survey conducted by the Australian Association of Clinical Biochemists Porphyrin Working Party on urinary porphobilinogen screening showed good sensitivity (75-97.5%). This is contrary to reports in the literature and to our own observations. We therefore assessed a widely used screening method (Watson-Schwartz) and found poor sensitivity (40-69%), and even less sensitivity (28-53%) when the urine samples were normally coloured or concentrated. Thus the results obtained by the Working Party might mislead one to infer that the Watson-Schwartz method is reliable.

引用

页码：197 / 198

页数：2