COMPOSITE OF A AND F-TYPE 5' TERMINAL SEQUENCES DEFINES A SUBFAMILY OF MOUSE LINE-1 ELEMENTS

被引：17

作者：

ADEY, NB ^{[1
]}

SCHICHMAN, SA ^{[1
]}

HUTCHISON, CA ^{[1
]}

EDGELL, MH ^{[1
]}

机构：

[1] UNIV N CAROLINA,DEPT MICROBIOL & IMMUNOL,CURRICULUM GENET,PROGRAM MOLEC BIOL & BIOTECHNOL,CHAPEL HILL,NC 72599

来源：

JOURNAL OF MOLECULAR BIOLOGY | 1991年 / 221卷 / 02期

关键词：

L1; EVOLUTION; SUBFAMILIES; MOUSE; 5'MOTIF;

D O I：

10.1016/0022-2836(91)80057-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The 5′ terminus of full-length L1 elements contains transcriptional control sequences. In mouse L1 (L1Md) elements, these sequenes exist as an array of tandem direct repeats. Two types of repeat units, termed A-monomers and F-monomers, have been reported. Both monomers are about 200 bp in length but share no significant sequence homology. Previous studies have identified L1Md elements containing either A or F-monomers but not both. Here we describe three "composite" L1Md elements that contain both types of monomer sequence. Two of these composite L1Md elements are highly homologous and share the same structural rearrangements, implying that they arose from a common ancestor that has the same composite 5′ end. © 1991.

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页码：367 / 373

页数：7

相关论文

共 36 条

[1] NUCLEOTIDE-SEQUENCE OF A MOUSE FULL-LENGTH F-TYPE L1 ELEMENT [J].

ADEY, NB ;

COMER, MB ;

EDGELL, MH ;

HUTCHISON, CA .

NUCLEIC ACIDS RESEARCH, 1991, 19 (09) :2497-2497

[2]

BANKIER AT, 1987, METHOD ENZYMOL, V155, P51

[3] DUPLICATED REGION OF THE MOUSE GENOME CONTAINING A CYTOPLASMIC GAMMA-ACTIN PROCESSED PSEUDOGENE ASSOCIATED WITH LONG INTERSPERSED REPETITIVE ELEMENTS [J].

BEGG, CE ;

DELIUS, H ;

LEADER, DP .

JOURNAL OF MOLECULAR BIOLOGY, 1988, 203 (03) :677-687

[4] CONSERVATION THROUGHOUT MAMMALIA AND EXTENSIVE PROTEIN-ENCODING CAPACITY OF THE HIGHLY REPEATED DNA LONG INTERSPERSED SEQUENCE ONE [J].

BURTON, FH ;

LOEB, DD ;

VOLIVA, CF ;

MARTIN, SL ;

EDGELL, MH ;

HUTCHISON, CA .

JOURNAL OF MOLECULAR BIOLOGY, 1986, 187 (02) :291-304

[5] EXTENSIVE MOVEMENT OF LINES ONE SEQUENCES IN BETA-GLOBIN LOCI OF MUS-CAROLI AND MUS-DOMESTICUS [J].

CASAVANT, NC ;

HARDIES, SC ;

FUNK, FD ;

COMER, MB ;

EDGELL, MH ;

HUTCHISON, CA .

MOLECULAR AND CELLULAR BIOLOGY, 1988, 8 (11) :4669-4674

[6] CHARACTERIZATION OF A 3RD MAJOR SINE FAMILY OF REPETITIVE SEQUENCES IN THE GALAGO GENOME [J].

DANIELS, GR ;

DEININGER, PL .

NUCLEIC ACIDS RESEARCH, 1991, 19 (07) :1649-1656

[7] A COMPREHENSIVE SET OF SEQUENCE-ANALYSIS PROGRAMS FOR THE VAX [J].

DEVEREUX, J ;

HAEBERLI, P ;

SMITHIES, O .

NUCLEIC ACIDS RESEARCH, 1984, 12 (01) :387-395

[8] SIZE AND STRUCTURE OF THE HIGHLY REPETITIVE BAM HI ELEMENT IN MICE [J].

FANNING, TG .

NUCLEIC ACIDS RESEARCH, 1983, 11 (15) :5073-5091

[9] LINE-1 - A MAMMALIAN TRANSPOSABLE ELEMENT [J].

FANNING, TG ;

SINGER, MF .

BIOCHIMICA ET BIOPHYSICA ACTA, 1987, 910 (03) :203-212

[10] THE STRUCTURE OF THE REGULATORY REGION OF THE RAT L1 (L1RN, LONG INTERSPERSED REPEATED) DNA FAMILY OF TRANSPOSABLE ELEMENTS [J].

FURANO, AV ;

ROBB, SM ;

ROBB, FT .

NUCLEIC ACIDS RESEARCH, 1988, 16 (19) :9215-9230

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