PHYSICAL AND LUBRICATION PROPERTIES OF MAGNESIUM STEARATE

被引：48

作者：

LEINONEN, UI ^{[1
]}

JALONEN, HU ^{[1
]}

VIHERVAARA, PA ^{[1
]}

LAINE, ESU ^{[1
]}

机构：

[1] UNIV TURKU,DEPT PHYS SCI,SF-20500 TURKU 50,FINLAND

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1992年 / 81卷 / 12期

关键词：

D O I：

10.1002/jps.2600811214

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The lubrication properties of two commercial-grade magnesium stearates were studied. Their moisture contents and crystal structures were similar. There were minor differences in their fatty acid composition, but the differences did not affect the lubrication properties. The lubrication properties correlated with particle size distributions and specific surface area. The effect of these parameters was further studied with unmilled and milled chemically pure magnesium stearate. Milling decreased the particle size and increased the specific surface area. In both cases, the batch with a smaller particle size and larger specific surface area had considerably better lubricity.

引用

页码：1194 / 1198

页数：5

共 8 条

[1] THE EFFECT OF THE VARIABILITY IN THE PHYSICAL AND CHEMICAL-PROPERTIES OF MAGNESIUM STEARATE ON THE PROPERTIES OF COMPRESSED TABLETS [J].