ADSORPTIVE STRIPPING VOLTAMMETRIC PROPERTIES OF FENTANYL AT HG ELECTRODE

Cyclic voltammetry shows that in a supporting electrolyte of NaOH, fentanyl (FENT) has a pair of cathodic and anodic peaks at Hg electrode. The peak potentials, E(pc) an E(pa), are -1.47 and -1.44 V (vs. Ag/AgCl), respectively. Fentanyl can be adsorbed on Hg surface, so the cathodic peak shows adsorptive properties. The adsorptive characteristics of fentanyl are explored in detail with various methods. The adsorbed species is considered to be fentanyl neutral molecule. The method for measuring trace amount of fentanyl by adsorptive stripping voltammetry is established. Under the optimised condition, the detection limit may reach 5 x 10(-8) M with a 10-min preconcentration.