LOCALIZATION OF THE 9P MELANOMA SUSCEPTIBILITY LOCUS (MLM) TO A 2-CM REGION BETWEEN D9S736 AND D9S171

被引：46

作者：

CANNONALBRIGHT, LA

GOLDGAR, DE

NEUHAUSEN, S

GRUIS, NA

ANDERSON, DE

LEWIS, CM

JOST, M

TRAN, TD

NYGUEN, K

KAMB, A

WEAVERFELDHAUS, J

MEYER, LJ

ZONE, JJ

SKOLNICK, MH

机构：

[1] UNIV UTAH,SCH MED,DEPT INTERNAL MED,DIV HEMATOL ONCOL,SALT LAKE CITY,UT 84108

[2] UNIV UTAH,SCH MED,DEPT MED INFORMAT,SALT LAKE CITY,UT 84108

[3] UNIV UTAH,SCH MED,DEPT INTERNAL MED,DIV DERMATOL,SALT LAKE CITY,UT 84108

[4] LEIDEN UNIV HOSP,DEPT DERMATOL,LEIDEN,NETHERLANDS

[5] LEIDEN UNIV,MGC,DEPT HUMAN GENET,LEIDEN,NETHERLANDS

[6] MYRIAD GENET,SALT LAKE CITY,UT 84108

[7] UNIV TEXAS,MD ANDERSON CANC CTR,DEPT MOLEC GENET,HOUSTON,TX 77030

[8] VET ADM MED CTR,CTR GERIATR RES EDUC & CLIN,SALT LAKE CITY,UT

来源：

GENOMICS | 1994年 / 23卷 / 01期

关键词：

D O I：

10.1006/geno.1994.1491

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A familial melanoma susceptibility locus (MLM) was identified on the short arm of chromosome 9 in a set of Utah and Texas kindreds. Subsequent confirmation was reported for a set of 26 Australian kindreds, a set of 7 Dutch kindreds, and a set of 13 NIH melanoma kindreds. The original localization report placed the locus near the IFNA-D9S126 interval on chromosome 9p. We report further localization using D9S171 and a newly developed marker, D9S736, both of which lie in the IFNA-D9S126 interval. Analysis of this set of kindreds places the melanoma susceptibility locus in a 2-cM region that is proximal to D9S736 and distal to D9S171. (C) 1994 Academic Press, Inc.

引用

页码：265 / 268

页数：4

共 22 条

[1] MAPPING THE GENE FOR HEREDITARY CUTANEOUS MALIGNANT-MELANOMA DYSPLASTIC NEVUS TO CHROMOSOME-1P [J].

BALE, SJ ;

DRACOPOLI, NC ;

TUCKER, MA ;

CLARK, WH ;

FRASER, MC ;

STANGER, BZ ;

GREEN, P ;

DONISKELLER, H ;

HOUSMAN, DE ;

GREENE, MH .

NEW ENGLAND JOURNAL OF MEDICINE, 1989, 320 (21) :1367-1372

[2]

CANNONALBRIGHT LA, 1990, AM J HUM GENET, V46, P912

[3] ASSIGNMENT OF A LOCUS FOR FAMILIAL MELANOMA, MLM, TO CHROMOSOME-9P13-P22 [J].

CANNONALBRIGHT, LA ;

GOLDGAR, DE ;

MEYER, LJ ;

LEWIS, CM ;

ANDERSON, DE ;

FOUNTAIN, JW ;

HEGI, ME ;

WISEMAN, RW ;

PETTY, EM ;

BALE, AE ;

OLOPADE, OI ;

DIAZ, MO ;

KWIATKOWSKI, DJ ;

PIEPKORN, MW ;

ZONE, JJ ;

SKOLNICK, MH .

SCIENCE, 1992, 258 (5085) :1148-1152

[4] CYTOGENETIC ANALYSIS OF MELANOCYTES FROM PREMALIGNANT NEVI AND MELANOMAS [J].

COWAN, JM ;

HALABAN, R ;

FRANCKE, U .

JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1988, 80 (14) :1159-1164

[5] A GENETIC-LINKAGE MAP OF THE HUMAN GENOME [J].

DONISKELLER, H ;

GREEN, P ;

HELMS, C ;

CARTINHOUR, S ;

WEIFFENBACH, B ;

STEPHENS, K ;

KEITH, TP ;

BOWDEN, DW ;

SMITH, DR ;

LANDER, ES ;

BOTSTEIN, D ;

AKOTS, G ;

REDIKER, KS ;

GRAVIUS, T ;

BROWN, VA ;

RISING, MB ;

PARKER, C ;

POWERS, JA ;

WATT, DE ;

KAUFFMAN, ER ;

BRICKER, A ;

PHIPPS, P ;

MULLERKAHLE, H ;

FULTON, TR ;

NG, S ;

SCHUMM, JW ;

BRAMAN, JC ;

KNOWLTON, RG ;

BARKER, DF ;

CROOKS, SM ;

LINCOLN, SE ;

DALY, MJ ;

ABRAHAMSON, J .

CELL, 1987, 51 (02) :319-337

[6]

FOUNTAIN JW, 1990, CANCER SURV, V9, P645

[7] HOMOZYGOUS DELETIONS WITHIN HUMAN-CHROMOSOME BAND-9P21 IN MELANOMA [J].

FOUNTAIN, JW ;

KARAYIORGOU, M ;

ERNSTOFF, MS ;

KIRKWOOD, JM ;

VLOCK, DR ;

TITUSERNSTOFF, L ;

BOUCHARD, B ;

VIJAYASARADHI, S ;

HOUGHTON, AN ;

LAHTI, J ;

KIDD, VJ ;

HOUSMAN, DE ;

DRACOPOLI, NC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (21) :10557-10561

[8]

FOUNTAIN JW, 1991, AM J HUM GENET S, V49, pA223

[9]

GOLDSTEIN AM, 1994, AM J HUM GENET, V54, P489

[10]

GOLDSTEIN AM, 1993, AM J HUM GENET, V52, P537

← 1 2 3 →