NEW APPROACH TO CHIRAL 5,5-DISUBSTITUTED 2-PYRROLIDINONES FROM (S)-PYROGLUTAMIC ACID

被引：17

作者：

NAGASAKA, T

IMAI, T

机构：

[1] Tokyo University of Pharmacy and Life Science, School of Pharmacy, Hachioji, Tokyo, 192-03

来源：

HETEROCYCLES | 1995年 / 41卷 / 09期

关键词：

D O I：

10.3987/COM-95-7159

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two enantiomers of 5,5-disubstituted 2-pyrrolidinones with the certain configurations were synthesized, starting from (S)-pyroglutamic acid, via the bicyclic lactam, (2R, 5S)-2-aryl-1-aza-3-oxabicyclo[3.3.0]oct-5-en-7-one (6).

引用

页码：1927 / 1930

页数：4

共 10 条

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