EVALUATION OF THE USE OF THE TERT-BUTYLDIMETHYLSILYL GROUP FOR 2'-PROTECTION IN RNA-SYNTHESIS VIA THE H-PHOSPHONATE APPROACH

被引：16

作者：

STAWINSKI, J ^{[1
]}

STROMBERG, R ^{[1
]}

THELIN, M ^{[1
]}

WESTMAN, E ^{[1
]}

机构：

[1] UNIV STOCKHOLM,ARRHENIUS LAB,DEPT ORGAN CHEM,S-10691 STOCKHOLM,SWEDEN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1988年 / 7卷 / 5-6期

关键词：

D O I：

10.1080/07328318808056329

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：779 / 782

页数：4

共 5 条

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[2]

JAGER A, 1987, NUCL ACIDS RES S SER, V18, P197

[3] THE FINAL DEPROTECTION STEP IN OLIGONUCLEOTIDE SYNTHESIS IS REDUCED TO A MILD AND RAPID AMMONIA TREATMENT BY USING LABILE BASE-PROTECTING GROUPS [J].

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MOLKO, D ;

TEOULE, R .

NUCLEIC ACIDS RESEARCH, 1987, 15 (02) :397-416

[4] SOLID-PHASE SYNTHESIS OF OLIGORIBONUCLEOTIDES USING THE O-NITROBENZYL GROUP FOR 2'-HYDROXYL PROTECTION AND H-PHOSPHONATE CHEMISTRY [J].

TANAKA, T ;

TAMATSUKURI, S ;

IKEHARA, M .

NUCLEIC ACIDS RESEARCH, 1987, 15 (18) :7235-7248

[5] AUTOMATED CHEMICAL SYNTHESIS OF LONG OLIGORIBONUCLEOTIDES USING 2'-O-SILYLATED RIBONUCLEOSIDE 3'-O-PHOSPHORAMIDITES ON A CONTROLLED-PORE GLASS SUPPORT - SYNTHESIS OF A 43-NUCLEOTIDE SEQUENCE SIMILAR TO THE 3'-HALF MOLECULE OF AN ESCHERICHIA-COLI FORMYLMETHIONINE TRANSFER-RNA [J].

USMAN, N ;

OGILVIE, KK ;

JIANG, MY ;

CEDERGREN, RJ .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (25) :7845-7854

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