SYNTHESIS AND PRELIMINARY DNA-INTERACTION STUDIES OF A NEW CATIONIC PORPHYRIN

被引:23
作者
ROBIC, N
BIEDCHARRETON, C
PERREFAUVET, M
VERCHEREBEAUR, C
SALMON, L
GAUDEMER, A
机构
[1] UNIV PARIS 11,ICMO,CNRS,CHIM BIOORGAN & BIOINORGAN LAB,BAT 420,F-91405 ORSAY,FRANCE
[2] SWARTHMORE COLL,SWARTHMORE,PA 19081
关键词
D O I
10.1016/S0040-4039(00)97720-7
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A new water-soluble porphyrin containing benzyl-trimethylammonium groups was synthesized in a two-step sequence from tetraphenylporphyrin and preliminary studies show that it binds strongly to DNA in an outside manner and gives fairly stable complexes with nucleotides and nucleosides. © 1990.
引用
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页码:4739 / 4742
页数:4
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