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OCULAR ANTIGENS .10. BOVINE RHODOPSIN AND ALPHA-CRYSTALLIN - STUDY OF THEIR IMMUNOGENICITY IN THE RABBIT AND ANTIGENIC RELATIONSHIPS WITH VARIOUS OCULAR-TISSUES

被引：4
作者：
BRINKMAN, CJJ
OERLEMANSVANZUTPHEN, MPJ
BROEKHUYSE, RM
机构：
[1] Institute of Ophthalmology, University of Nijmegen, Nijmegen
来源：
EXPERIMENTAL EYE RESEARCH | 1979年 / 29卷 / 06期
关键词：
antigenic determinants; immunodiffusion; immunogenicity; lymphocyte stimulation; rhodopsin; skin test; α-crystallin;
D O I：
10.1016/0014-4835(79)90016-2
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Rabbits were sensitized with highly purified bovine α-crystallin and rhodopsin. Without boosting, α-crystallin predominantly stimulated the humoral immune system, and rhodopsin predominantly the cellular immune system. The results obtained by lymphocyte stimulation tests, skin tests and immunodiffusion point to the presence of α-crystallin determinants in bovine iris and probably in choroid, but not in cornea and retina. Rhodopsin determinants have been detected in cornea and sclera, while they seem to lack in lens and iris. © 1979.
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页码：609 / 617
页数：9
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