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METHODS TO STUDY PEPTIDES ASSOCIATED WITH MHC CLASS-I MOLECULES

被引：43
作者：
JOYCE, S
NATHENSON, SC
机构：
[1] ALBERT EINSTEIN COLL MED,DEPT MICROBIOL & IMMUNOL,BRONX,NY 10411
[2] ALBERT EINSTEIN COLL MED,DEPT CELL BIOL,BRONX,NY 10411
来源：
CURRENT OPINION IN IMMUNOLOGY | 1994年 / 6卷 / 01期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0952-7915(94)90029-9
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
It is now an accepted fact that peptides of self or non-self origin form an essential component of the MHC class I structure. The peptide component of the heterotrimer contains the essential determinants recognized by the T-cell receptors of cytotoxic T lymphocytes, be it an antigen-specific, alloimmune or autoimmune response. Because of the importance of the recognition process, several methods have been developed to characterize naturally processed peptides presented by the class I molecules.
引用
收藏
页码：24 / 31
页数：8
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