A SIMPLIFIED PLAQUE REDUCTION ASSAY FOR ANTIVIRAL AGENTS FROM PLANTS - DEMONSTRATION OF FREQUENT OCCURRENCE OF ANTIVIRAL ACTIVITY IN HIGHER-PLANTS

被引：51

作者：

ABOUKARAM, M ^{[1
]}

SHIER, WT ^{[1
]}

机构：

[1] UNIV MINNESOTA,COLL PHARM,DEPT MED CHEM,MINNEAPOLIS,MN 55455

来源：

JOURNAL OF NATURAL PRODUCTS | 1990年 / 53卷 / 02期

关键词：

D O I：

10.1021/np50068a011

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

An improved plaque reduction assay for antiviral activity was developed and used to examine extracts from sixty-one higher plants. Substantial antiviral activity was observed in ca. 20%, which is higher than might be expected given the limited metabolic differences between viruses and their hosts. The frequent antiviral activity may represent phytoalexins elaborated to protect against plant viruses. © 1990, American Chemical Society. All rights reserved.

引用

页码：340 / 344

页数：5

共 8 条

[1] ABBAS HK, 1984, J ASSOC OFF ANA CHEM, V67, P607
[2] Bailey J. A., 1982, PHYTOALEXINS
[3] FARNSWORTH NR, 1968, LLOYD, V31, P237
[4] FARNSWORTH NR, 1966, LLOYD, V29, P101
[5] SHIER WT, 1983, AM J PHARM EDUC, V47, P216
[6] ETHNOPHARMACOLOGICAL ANALYSIS OF MEDICINAL-PLANTS USED BY LAOTIAN HMONG REFUGEES IN MINNESOTA
SPRING, MA
[J]. JOURNAL OF ETHNOPHARMACOLOGY, 1989, 26 (01) : 65 - 91
[7] VANDENBERGHE DA, 1978, LLOYDIA, V41, P463
[8] VANDENBERGHE DA, 1986, B I PASTEUR, V84, P101

← 1 →