IMPROVED METHOD FOR OPTICAL PURITY DETERMINATION OF KETAZOLAM WITH CHIRAL SHIFT-REAGENT

被引：6

作者：

LAPLANCHE, LA ^{[1
]}

ROTHCHILD, R ^{[1
]}

机构：

[1] CUNY JOHN JAY COLL CRIMINAL JUSTICE,CTR TOXICOL RES & TRAINING,DEPT SCI,NEW YORK,NY 10019

来源：

SPECTROSCOPY LETTERS | 1990年 / 23卷 / 01期

基金：

美国国家科学基金会;

关键词：

Chiral; Enantiomer; Ketazolam; Lanthanide; NMR shift reagents; Optical Purity; Yb(HFC)3;

D O I：

10.1080/00387019008054035

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

An improved method for direct determination of optical purity of the novel benzodiazepine analog, ketazolam, 1, is reported. Adding the chiral lanthanide NMR shift reagent, tris[3-(hepta-. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：45 / 64

页数：20

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