CEREBRAL MRI IN 2 BROTHERS WITH MUCOPOLYSACCHARIDOSIS TYPE-I AND DIFFERENT CLINICAL PHENOTYPES

被引：14

作者：

GABRIELLI, O

SALVOLINI, U

MARICOTTI, M

MARIANI, MG

COPPA, GV

GIORGI, PL

机构：

[1] UNIV ANCONA,DEPT NEURORADIOL,I-60123 ANCONA,ITALY

[2] UNIV ANCONA,DEPT NEUROL,I-60123 ANCONA,ITALY

来源：

NEURORADIOLOGY | 1992年 / 34卷 / 04期

关键词：

CEREBRAL MAGNETIC RESONANCE IMAGING; MENTAL RETARDATION; MUCOPOLYSACCHARIDOSES; ALPHA-L-IDURONIDASE DEFICIENCY;

D O I：

10.1007/BF00588189

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We describe a cerebral MRI study of two brothers with mucopolysaccharidosis type I. They are of similar physical appearance, but the younger is severely mentally retarded while the elder is of normal intelligence. MRI shows characteristic abnormalities in the CNS, but it is not yet possible to establish a correlation between them and the mental retardation.

引用

页码：313 / 315

页数：3

共 17 条

[1]

CROME L, 1972, PATHOLOGY MENTAL RET, P320

[2] MUCOPOLYSACCHARIDOSIS TYPES-1, TYPE-2, TYPE-3A AND TYPE-5 - PATHOLOGICAL AND BIOCHEMICAL ABNORMALITIES IN NEURAL AND MESENCHYMAL ELEMENTS OF BRAIN [J].