MOLECULAR EPIDEMIOLOGY OF RESPIRATORY SYNCYTIAL VIRUS - RAPID IDENTIFICATION OF SUBGROUP-A LINEAGES

被引:61
作者
CANE, PA
PRINGLE, CR
机构
[1] Department of Biological Sciences, University of Warwick, Coventry
基金
英国医学研究理事会;
关键词
RS-VIRUS; CLASSIFICATION; RESTRICTION MAPPING; G-GENE;
D O I
10.1016/0166-0934(92)90088-U
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Methods for the rapid analysis of samples of respiratory syncytial (RS) virus are described using the polymerase chain reaction (PCR) followed by restriction mapping. Isolates (either clinical samples or tissue culture grown virus) can readily be divided into subgroups and then further classified into lineages. These methods enable examination of large numbers of isolates by molecular techniques, thereby facilitating research into the molecular epidemiology of the virus.
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页码:297 / 306
页数:10
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