学术探索
学术期刊
新闻热点
数据分析
智能评审

CHOLESTERYL-CONJUGATED OLIGONUCLEOTIDES - SYNTHESIS, PROPERTIES, AND ACTIVITY AS INHIBITORS OF REPLICATION OF HUMAN IMMUNODEFICIENCY VIRUS IN CELL-CULTURE

被引：326
作者：
LETSINGER, RL
ZHANG, GG
SUN, DK
IKEUCHI, T
SARIN, PS
机构：
[1] NW UNIV,DEPT BIOCHEM MOLEC BIOL & CELL BIOL,EVANSTON,IL 60208
[2] NCI,TUMOR CELL BIOL LAB,BETHESDA,MD 20892
来源：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1989年 / 86卷 / 17期
关键词：
D O I：
10.1073/pnas.86.17.6553
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
引用
收藏
页码：6553 / 6556
页数：4
相关论文
共 24 条
  • [1] OLIGODEOXYNUCLEOSIDE PHOSPHORAMIDATES AND PHOSPHOROTHIOATES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS
    AGRAWAL, S
    GOODCHILD, J
    CIVEIRA, MP
    THORNTON, AH
    SARIN, PS
    ZAMECNIK, PC
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (19) : 7079 - 7083
  • [2] INHIBITION OF VESICULAR STOMATITIS-VIRUS PROTEIN-SYNTHESIS AND INFECTION BY SEQUENCE-SPECIFIC OLIGODEOXYRIBONUCLEOSIDE METHYLPHOSPHONATES
    AGRIS, CH
    BLAKE, KR
    MILLER, PS
    REDDY, MP
    TSO, POP
    [J]. BIOCHEMISTRY, 1986, 25 (20) : 6268 - 6275
  • [3] BARRETT JC, 1974, BIOCHEMISTRY-US, V12, P4898
  • [4] CARUTHERS MH, 1982, GENETIC ENG, V4, P1
  • [5] LIPIDS ARE MAJOR COMPONENTS OF HUMAN IMMUNODEFICIENCY VIRUS (HIV) - MODIFICATION OF HIV LIPID-COMPOSITION, MEMBRANE ORGANIZATION, AND PROTEIN CONFORMATION BY AL-721
    CREWS, FT
    MCELHANEY, MR
    KLEPNER, CA
    LIPPA, AS
    [J]. DRUG DEVELOPMENT RESEARCH, 1988, 14 (01) : 31 - 44
  • [6] DEOXYNUCLEOSIDE H-PHOSPHONATE DIESTER INTERMEDIATES IN THE SYNTHESIS OF INTERNUCLEOTIDE PHOSPHATE ANALOGS
    FROEHLER, BC
    [J]. TETRAHEDRON LETTERS, 1986, 27 (46) : 5575 - 5578
  • [7] SYNTHESIS OF DNA VIA DEOXYNUCLEOSIDE H-PHOSPHONATE INTERMEDIATES
    FROEHLER, BC
    NG, PG
    MATTEUCCI, MD
    [J]. NUCLEIC ACIDS RESEARCH, 1986, 14 (13) : 5399 - 5407
  • [8] INHIBITION OF HUMAN IMMUNODEFICIENCY VIRUS-REPLICATION BY ANTISENSE OLIGODEOXYNUCLEOTIDES
    GOODCHILD, J
    AGRAWAL, S
    CIVEIRA, MP
    SARIN, PS
    SUN, D
    ZAMECNIK, PC
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (15) : 5507 - 5511
  • [9] GOODCHILD J, 1988, UCLA S MOL CELLULAR, V77, P423
  • [10] THE ROLE OF ANTISENSE RNA IN GENE-REGULATION
    GREEN, PJ
    PINES, O
    INOUYE, M
    [J]. ANNUAL REVIEW OF BIOCHEMISTRY, 1986, 55 : 569 - 597
123