REGIOSELECTIVE HYDROXYLATION OF WARFARIN BY CELL-SUSPENSION CULTURES OF CATHARANTHUS-ROSEUS

被引：17

作者：

HAMADA, H ^{[1
]}

FUCHIKAMI, Y ^{[1
]}

JANSING, RL ^{[1
]}

KAMINSKY, LS ^{[1
]}

机构：

[1] NEW YORK STATE DEPT HLTH,WADSWORTH CTR LABS & RES,ALBANY,NY 12201

来源：

PHYTOCHEMISTRY | 1993年 / 33卷 / 03期

关键词：

CATHARANTHUS-ROSEUS; BIOTRANSFORMATION; WARFARIN; REGIOSELECTIVE HYDROXYLATION; ANTICOAGULANT; RODENTICIDE; REDUCTION; CELL SUSPENSION CULTURES;

D O I：

10.1016/0031-9422(93)85454-Y

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Cell suspension cultures of Catharanthus roseus reduce the carbonyl group of warfarin to the corresponding alcohol and regioselectively hydroxylate warfarin.

引用

页码：599 / 600

页数：2

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