MITOMYCIN ANTIBIOTICS - SYNTHESIS OF 7-METHOXY-1-(N-PYRROLIDINO)MITOSENE AND ITS METHIODIDE

被引：7

作者：

MOTT, J ^{[1
]}

REMERS, WA ^{[1
]}

机构：

[1] PURDUE UNIV,SCH PHARM & PHARM SCI,DEPT MED CHEM & PHARMACOGNOSY,W LAFAYETTE,IN 47907

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1978年 / 21卷 / 05期

关键词：

D O I：

10.1021/jm00203a020

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：493 / 495

页数：3

共 9 条

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ALLEN, GR ;

BINOVI, LJ ;

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[2] MITOMYCIN ANTIBIOTICS . SYNTHETIC STUDIES .2. SYNTHESIS OF 7-METHOXYMITOSENE ANTIBACTERIAL AGENT [J].

ALLEN, GR ;

POLETTO, JF ;

WEISS, MJ .

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[3] SYNTHESIS AND ANTILEUKEMIC ACTIVITY OF 5-SUBSTITUTED 2,3-DIHYDRO-6,7-BIS(HYDROXYMETHYL)-1H-PYRROLIZINE DIESTERS [J].

ANDERSON, WK ;

COREY, PF .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (06) :812-818

[4]

FOST DL, 1973, TETRAHEDRON LETT, P131

[5] STRUCTURE-ACTIVITY-RELATIONSHIPS OF MITOMYCINS AND CERTAIN SYNTHETIC ANALOGS [J].

REMERS, WA ;

SCHEPMAN, CS .

JOURNAL OF MEDICINAL CHEMISTRY, 1974, 17 (07) :729-732

[6] MITOMYCIN ANTIBIOTICS . SYNTHETIC STUDIES .8. NITRATION AND O-BENZYL REARRANGEMENT IN 7-OXYPYRROLOINDOLE SYSTEM [J].

REMERS, WA ;

ROTH, RH ;

WEISS, MJ .

JOURNAL OF ORGANIC CHEMISTRY, 1965, 30 (12) :4381-&

[7]

Szybalski W., 1967, ANTIBIOTICS, V1, P211

[8] MITOMYCIN ANTIBIOTICS - SYNTHESIS AND ACTIVITY OF 1,2-DISUBSTITUTED MITOSENES [J].

TAYLOR, WG ;

LEADBETTER, G ;

FOST, DL ;

REMERS, WA .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (01) :138-141

[9]

1972, CANCER CHEMOTHER R 3, V3, P9

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