ASSIGNMENT OF CASEIN KINASE-2-ALPHA SEQUENCES TO 2 DIFFERENT HUMAN-CHROMOSOMES

被引：8

作者：

BOLDYREFF, B

KLETT, C

GOTTERT, E

VANKESSEL, AG

HAMEISTER, H

ISSINGER, OG

机构：

[1] UNIV SAARLAND,INST HUMANGENET,W-6650 HOMBURG 3,GERMANY

[2] UNIV HOSP NIJMEGEN,DEPT HUMAN GENET,6500 HB NIJMEGEN,NETHERLANDS

[3] UNIV ULM,KLIN GENET ABT,W-7900 ULM,GERMANY

来源：

HUMAN GENETICS | 1992年 / 89卷 / 01期

关键词：

D O I：

10.1007/BF00207047

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Human casein kinase 2 alpha gene (CK-2-alpha) sequences have been localized within the human genome by in situ hybridization and somatic cell hybrid analysis using a CK-2 alpha cDNA as a probe. By in situ hybridization, the CK-2 alpha cDNA could be assigned to two different loci, one on llpl5.1-ter and one on 20p13. The existence of two separate chromosomal loci suggests that CK-2 alpha is a member of a gene family. Only the locus on chromosome 11 was confirmed by somatic cell hybrid analysis. The analysis was based on the presence of a CK-2-alpha-specific 20-kb fragment. However, the CK-2 alpha cDNA hybridizes to several additional fragments in total human DNA.

引用

页码：79 / 82

页数：4

共 16 条

[1] A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY
FEINBERG, AP
VOGELSTEIN, B
[J]. ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) : 6 - 13
[2] ISOLATION AND CHARACTERIZATION OF RECOMBINANT HUMAN CASEIN KINASE-II SUBUNITS ALPHA AND BETA FROM BACTERIA
GRANKOWSKI, N
BOLDYREFF, B
ISSINGER, OG
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1991, 198 (01): : 25 - 30
[3] CLONING AND CHARACTERIZATION OF A CDNA-ENCODING THE BETA-SUBUNIT OF HUMAN CASEIN KINASE-II
HELLERHARRISON, RA
MEISNER, H
CZECH, MP
[J]. BIOCHEMISTRY, 1989, 28 (23) : 9053 - 9058
[4] CASEIN KINASE-II AS A POTENTIALLY IMPORTANT ENZYME CONCERNED WITH SIGNAL TRANSDUCTION
KREBS, EG
EISENMAN, RN
KUENZEL, EA
LITCHFIELD, DW
LOZEMAN, FJ
LUSCHER, B
SOMMERCORN, J
[J]. COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY, 1988, 53 : 77 - 84
[5] LOCALIZATION OF THE ACTIVE TYPE-I DNA TOPOISOMERASE GENE ON HUMAN CHROMOSOME-20Q11.2-13.1, AND 2 PSEUDOGENES ON CHROMOSOME-1Q23-24 AND CHROMOSOME-22Q11.2-13.1
KUNZE, N
YANG, GC
JIANG, ZY
HAMEISTER, H
ADOLPH, S
WIEDORN, KH
RICHTER, A
KNIPPERS, R
[J]. HUMAN GENETICS, 1989, 84 (01) : 6 - 10
[6] ISOLATION AND CHARACTERIZATION OF HUMAN CDNA CLONES ENCODING THE ALPHA-SUBUNIT AND THE ALPHA'-SUBUNIT OF CASEIN KINASE-II
LOZEMAN, FJ
LITCHFIELD, DW
PIENING, C
TAKIO, K
WALSH, KA
KREBS, EG
[J]. BIOCHEMISTRY, 1990, 29 (36) : 8436 - 8447
[7] MARIDOR G, 1991, J BIOL CHEM, V266, P2362
[8] MOLECULAR-CLONING OF THE HUMAN CASEIN KINASE-II ALPHA-SUBUNIT
MEISNER, H
HELLERHARRISON, R
BUXTON, J
CZECH, MP
[J]. BIOCHEMISTRY, 1989, 28 (09) : 4072 - 4076
[9] CASEIN KINASE-II IS ELEVATED IN SOLID HUMAN TUMORS AND RAPIDLY PROLIFERATING NONNEOPLASTIC TISSUE
MUNSTERMANN, U
FRITZ, G
SEITZ, G
LU, YP
SCHNEIDER, HR
ISSINGER, OG
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1990, 189 (02): : 251 - 257
[10] ISOLATION, SEQUENCING, AND DISRUPTION OF THE YEAST CKA2 GENE - CASEIN KINASE-II IS ESSENTIAL FOR VIABILITY IN SACCHAROMYCES-CEREVISIAE
PADMANABHA, R
CHENWU, JLP
HANNA, DE
GLOVER, CVC
[J]. MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (08) : 4089 - 4099

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