EPOXY RESIN BEADS AS A PHARMACEUTICAL DOSAGE FORM .I. METHOD OF PREPARATION

被引：25

作者：

KHANNA, SC

SPEISER, P

机构：

[1] School of Pharmacy, Federal Institute of Technology, Zurich

[2] Galenic Research Section., Basel

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1969年 / 58卷 / 09期

关键词：

Acids; bases–epoxy resin curing agents; Drug‐epoxy resin beads–preparation; Epoxy resin beads–dosage forms; UV spectrophotometry–analysis;

D O I：

10.1002/jps.2600580916

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The preparation of various epoxy resins containing acidic and basic curing agents was investigated. These resins were prepared in bead and bulk forms. The effects of the types of curing agents and their concentrations on the solubility of the resins artificial gastrointestinal juices have been studied. The addition basic and acidic curing agents in the resins was observed to influence their solubility in acidic and alkaline buffer, respectively. The method of preparation of these resins into bead forms was developed in the presence of drugs. Copyright © 1969 Wiley‐Liss, Inc., A Wiley Company

引用

页码：1114 / &