IMIPENEM PROPHYLAXIS IN ELECTIVE COLORECTAL SURGERY

被引：19

作者：

KARRAN, SJ ^{[1
]}

SUTTON, G ^{[1
]}

GARTELL, P ^{[1
]}

KARRAN, SE ^{[1
]}

FINNIS, D ^{[1
]}

BLENKINSOP, J ^{[1
]}

机构：

[1] SALISBURY ROYAL INFIRM,DEPT SURG,SALISBURY,ENGLAND

来源：

BRITISH JOURNAL OF SURGERY | 1993年 / 80卷 / 09期

关键词：

D O I：

10.1002/bjs.1800800946

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

In a randomized controlled study of 411 patients undergoing elective colorectal surgery, the efficacy and safety of two different regimens of imipenem were compared with those of a control regimen of cefuroxime plus metronidazole. Surgical infections occurred in 92 (26.4 per cent) of 349 evaluable patients. There were no major differences between the three treatment groups. It is concluded that imipenem is as effective as cefuroxime plus metronidazole in the prevention of sepsis after elective colorectal procedures.

引用

页码：1196 / 1198

页数：3

共 4 条

[1] COMPARISON OF ONE DOSE VERSUS 3 DOSES OF PROPHYLACTIC ANTIBIOTICS, AND THE INFLUENCE OF BLOOD-TRANSFUSION, ON INFECTIOUS COMPLICATIONS IN ACUTE AND ELECTIVE COLORECTAL SURGERY [J].