DIRECT CHARACTERIZATION OF THE SELECTIVITY OF FURAFYLLINE AS AN INHIBITOR OF HUMAN CYTOCHROMES P450 1A1 AND 1A2

被引：42

作者：

TASSANEEYAKUL, W

BIRKETT, DJ

VERONESE, ME

MCMANUS, ME

TUKEY, RH

MINERS, JO

机构：

[1] FLINDERS UNIV S AUSTRALIA,MED CTR,DEPT CLIN PHARMACOL,BEDFORD PK,SA 5042,AUSTRALIA

[2] UNIV QUEENSLAND,DEPT PHYSIOL & PHARMACOL,BRISBANE,QLD 4072,AUSTRALIA

[3] UNIV CALIF SAN DIEGO,CTR CANC,LA JOLLA,CA 92093

来源：

PHARMACOGENETICS | 1994年 / 4卷 / 05期

关键词：

D O I：

10.1097/00008571-199410000-00007

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：281 / 284

页数：4

共 12 条

[1]

BOOBIS AR, 1994, CANCER RES, V54, P89

[2] DETERMINATION OF CYP1A2 AND NAT2 PHENOTYPES IN HUMAN-POPULATIONS BY ANALYSIS OF CAFFEINE URINARY METABOLITES [J].

BUTLER, MA ;

LANG, NP ;

YOUNG, JF ;

CAPORASO, NE ;

VINEIS, P ;

HAYES, RB ;

TEITEL, CH ;

MASSENGILL, JP ;

LAWSEN, MF ;

KADLUBAR, FF .

PHARMACOGENETICS, 1992, 2 (03) :116-127

[3] OXIDATION OF TOXIC AND CARCINOGENIC CHEMICALS BY HUMAN CYTOCHROME-P-450 ENZYMES [J].

GUENGERICH, FP ;

SHIMADA, T .

CHEMICAL RESEARCH IN TOXICOLOGY, 1991, 4 (04) :391-407

[4]

KITZ R, 1962, J BIOL CHEM, V237, P3245

[5] ISOFORM-SELECTIVE MECHANISM-BASED INHIBITION OF HUMAN CYTOCHROME-P450 1A2 BY FURAFYLLINE [J].

KUNZE, KL ;

TRAGER, WF .

CHEMICAL RESEARCH IN TOXICOLOGY, 1993, 6 (05) :649-656

[6] LOCALIZATION OF CYP1A1 AND CYP1A2 MESSENGER-RNA IN NORMAL HUMAN LIVER AND IN HEPATOCELLULAR-CARCINOMA BY INSITU HYBRIDIZATION [J].

MCKINNON, RA ;

HALL, PD ;

QUATTROCHI, LC ;

TUKEY, RH ;

MCMANUS, ME .

HEPATOLOGY, 1991, 14 (05) :848-856

[7]

MCMANUS ME, 1990, CANCER RES, V50, P3367

[8]

PETERSEN DD, 1991, AM J HUM GENET, V48, P720

[9] FURAFYLLINE IS A POTENT AND SELECTIVE INHIBITOR OF CYTOCHROME-P450IA2 IN MAN [J].

SESARDIC, D ;

BOOBIS, AR ;

MURRAY, BP ;

MURRAY, S ;

SEGURA, J ;

DELATORRE, R ;

DAVIES, DS .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1990, 29 (06) :651-663

[10] ACCUMULATION OF CAFFEINE IN HEALTHY-VOLUNTEERS TREATED WITH FURAFYLLINE [J].

TARRUS, E ;

CAMI, J ;

ROBERTS, DJ ;

SPICKETT, RGW ;

CELDRAN, E ;

SEGURA, J .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1987, 23 (01) :9-18

← 1 2 →