2-BETA-(3-HYDROXYPROPOXY)-1-ALPHA,25-DIHYDROXYVITAMIN-D3 (ED-71), PREVENTIVE AND THERAPEUTIC EFFECTS ON BONE-MINERAL LOSS IN OVARIECTOMIZED RATS

被引：18

作者：

KOBAYASHI, T ^{[1
]}

OKANO, T ^{[1
]}

TSUGAWA, N ^{[1
]}

MURANO, M ^{[1
]}

MASUDA, S ^{[1
]}

TAKEUCHI, A ^{[1
]}

SATO, K ^{[1
]}

NISHII, Y ^{[1
]}

机构：

[1] CHUGAI PHARMACEUT CO LTD,TOSHIMA,TOKYO 171,JAPAN

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 09期

关键词：

D O I：

10.1016/S0960-894X(00)80111-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

2Beta-(3-hydroxypropoxy)-1alpha,25-dihydroxyvitamin D3 (ED-71) improved bone mineral density and mechanical bone strength in the pre-osteoporosis and osteoporosis model rats made by ovariectomy more effectively than 1alpha,25-dihydroxyvitamin D3.

引用

页码：1815 / 1819

页数：5

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