ABSORPTION AND METABOLISM OF PERMETHRIN AND CYPERMETHRIN IN THE COCKROACH AND THE COTTON-LEAFWORM LARVAE

被引:48
作者
HOLDEN, JS
机构
[1] ICI Ltd, Plant Protection Division, Jealott 's Hill Research Station, Bracknell, Berkshire
来源
PESTICIDE SCIENCE | 1979年 / 10卷 / 04期
关键词
D O I
10.1002/ps.2780100404
中图分类号
S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
Permethrin was metabolised by attack at the ester bond, in vivo by adult cockroaches, Periplaneta americana and in vitro by esterase preparations. Metabolites retaining the ester linkage could not be detected. In all cases, the (1RS)‐trans‐isomer (transpermethrin) was more labile than the (1RS)‐cis‐isomer. Cypermethrin was metabolised at one‐fifth the rate for permethrin. In‐vitro and in‐vivo studies with synergists indicated that cleavage of the ester bond in permethrin can be both oxidative for the (1RS)‐cis‐isomer and hydrolytic for the (1RS)‐trans‐isomer. The penetration of permethrin through the cuticle of the cockroach was significantly greater than that of cypermethrin. The penetration and metabolism of permethrin and cypermethrin in sixth‐instar larvae of susceptible and resistant strains of the Egyptian cotton‐leafworm, Spodoptera littoralis, were studied as possible factors in resistance. No significant differences were found. It is suggested that the major resistance factor to permethrin in S. littoralis is probably non‐metabolic. Copyright © 1979 John Wiley & Sons, Ltd
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页码:295 / 307
页数:13
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