ASYMMETRIC-SYNTHESIS OF ALPHA-HALO ESTERS

被引:40
作者
DURST, T [1 ]
KOH, K [1 ]
机构
[1] UNIV OTTAWA,OTTAWA CARLTON CHEM INST,DEPT CHEM,OTTAWA K1N 6N5,ONTARIO,CANADA
关键词
D O I
10.1016/S0040-4039(00)61779-3
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The reaction of (R)-Pantolactone with alpha-halogenated ketenes has been found to proceed with good to excellent diastereoselectivities (de 75 to > 95%). The (R)-Pantolacto chiral auxiliary induced the (S)-configuration at the new chiral center in most cases.
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页码:6799 / 6802
页数:4
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