A PALLADIUM-MEDIATED TANDEM CARBON-CARBON BOND-FORMING METHOD FEATURING NUCLEOPHILIC-SUBSTITUTION OF INTERMEDIATE PI-ALLYLPALLADIUM COMPLEXES PRODUCED VIA THE HECK REACTION

被引：10

作者：

NYLUND, CS ^{[1
]}

SMITH, DT ^{[1
]}

KLOPP, JM ^{[1
]}

WEINREB, SM ^{[1
]}

机构：

[1] PENN STATE UNIV,DEPT CHEM,UNIVERSITY PK,PA 16802

来源：

TETRAHEDRON | 1995年 / 51卷 / 34期

关键词：

D O I：

10.1016/0040-4020(95)00518-D

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Carbon nucleophiles are alkylated with pi-allylpalladium complexes formed by the palladium-catalyzed Heck reaction of a vinyl bromide and an olefin. This methodology achieves the consecutive formation of two carbon-carbon bonds in one simple operation and can be applied both inter- and intramolecularly. The rapid construction of functionalized carbobicyclic compounds is effected by the intramolecular version of this condensation.

引用

页码：9301 / 9318

页数：18

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