RETROVIRAL PSEUDOTYPES PRODUCED BY RESCUE OF A MOLONEY MURINE LEUKEMIA-VIRUS VECTOR BY C-TYPE, BUT NOT D-TYPE, RETROVIRUSES

被引：42

作者：

TAKEUCHI, Y

SIMPSON, G

VILE, RG

WEISS, RA

COLLINS, MKL

机构：

[1] INST CANC RES,CHESTER BEATTY LABS,237 FULHAM RD,LONDON SW3 6JB,ENGLAND

[2] GUNMA UNIV,SCH MED,DEPT HYG,MAEBASHI,GUNMA 371,JAPAN

来源：

VIROLOGY | 1992年 / 186卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1016/0042-6822(92)90049-U

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human HOS cells containing a Moloney murine leukemia virus (Mo-MLV) recombinant genome were infected by a panel of retroviruses. The C-type viruses simian sarcoma associated virus, feline leukemia virus subgroup B, and the feline endogenous virus RD114 were able to form pseudotypes with the Mo-MLV genome, which transferred a selectable marker gene to target cells; however, Human T cell leukemia virus-1 and the D-type viruses Mason-Pfizer monkey virus and simian retrovirus-1 failed to rescue the Mo-MLV vector. Further characterization of the RD114 pseudotype demonstrated that it retained the receptor specificity of RD114 and will therefore prove useful in receptor characterization. © 1992.

引用

页码：792 / 794

页数：3

共 35 条

[1] A PUTATIVE MURINE ECOTROPIC RETROVIRUS RECEPTOR GENE ENCODES A MULTIPLE MEMBRANE-SPANNING PROTEIN AND CONFERS SUSCEPTIBILITY TO VIRUS-INFECTION [J].