DIET AND PROSTATIC-CANCER - A CASE-CONTROL STUDY IN NORTHERN ITALY

被引：130

作者：

TALAMINI, R

FRANCESCHI, S

LAVECCHIA, C

SERRAINO, D

BARRA, S

NEGRI, E

机构：

[1] Epidemiology Unit, Aviano Cancer Center, 33081, Aviano, (PN)

[2] “Mario Negri” Institute for Pharmacological Research, 20157, Milan

[3] Institute of Social and Preventive Medecine, University of Lausanne, 1005, Lausanne

来源：

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL | 1992年 / 18卷 / 03期

关键词：

D O I：

10.1080/01635589209514228

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The relationship between intake of various indicator foods and beverages and risk of prostatic cancer was assessed in 271 cases of prostatic cancer and 685 hospital controls recruited in two areas of northern Italy, the province of Pordenone and the greater Milan area. Increased risks were found for more frequent intake of meat [odds ratio (OR) in the highest vs. lowest consumption tertile = 1.4, 95% confidence interval (CI) 1.0-2.0], milk (OR = 1.6, 95% CI 1.1-2.4), fresh fruit (OR = 1.4, 95% CI 1.0-2.1), and vegetables (OR = 1.4, 95% CI 0.9-2.2). After allowance for the reciprocal confounding effect of various dietary habits, only frequent intake of milk seemed to be a significant independent indicator of prostatic cancer risk. There was also a clue that the unfavorable influence of frequent intake of a few food items (i.e., meat, fish, liver, ham and salami, milk and butter, and retinol) may be greater or restricted to older individuals (i.e., greater-than-or-equal-to 70 yrs of age). In conclusion, the present study confirms the presence of a moderate adverse effect of high intake of foods of animal origin, chiefly milk, while it suggests that a diet rich in fresh fruit and vegetables does not convey a protection.

引用

页码：277 / 286

页数：10

共 48 条

[1] Muir C., Waterhouse J., Mack T., Powell J., Whelan S., Cancer Incidence in Five Continents, 5., (1987)
[2] Carter H.B., Coffey D.S., The Prostate: An Increasing Medical Problem., Prostate, 16, pp. 39-48, (1990)
[3] Levi F., Maisonneuve P., Filiberti R., La Vecchia C., Boyle P., Cancer Incidence and Mortality in Europe., Soz Praeventivmed, 34, pp. S1-S84, (1989)
[4] Mezzanotte G., Cislaghi C., Decarli A., La Vecchia C., Cancer Mortality in Broad Italian Geographical Areas, 1975–1977., Tumori 72, pp. 145-152, (1986)
[5] Cislaghi C., Decarli A., La Vecchia C., Laverda N., Mezzanotte G., Et al., Dati, Indicatori e Mappe di Mortalita Tumorale. Italia, pp. 1975-1977, (1986)
[6] Armstrong B., Doll R., Environmental Factors and Cancer Incidence and Mortality in Different Countries, With Special Reference to Dietary Practices., Int J Cancer, 15, pp. 617-631, (1975)
[7] Blair A., Fraumeni J.F., Geographic Patterns of Prostate Cancer in the United States., JNCI, 61, pp. 1379-1384, (1978)
[8] Zaridze D.G., Boyle P., Cancer of the Prostate: Epidemiology and Aetiology., Br J Urol, 59, pp. 493-502, (1987)
[9] Decarli A., La Vecchia C., Environmental Factors and Cancer Mortality in Italy: Correlational Exercise., Oncology, 43, pp. 116-126, (1986)
[10] Rotkin I.D., Studies in the Epidemiology of Prostate Cancer: Expanded Sampling., Cancer Treat Rep, 61, pp. 173-180, (1977)

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