FOLLOW-UP OF PATIENTS WITH DOUBLE-STRANDED DNA ANTIBODIES INDUCED BY SULFASALAZINE DURING THE TREATMENT OF INFLAMMATORY RHEUMATIC DISEASES

被引：10

作者：

MIELKE, H

WILDHAGEN, K

MAU, W

ZEIDLER, H

机构：

[1] HANNOVER MED SCH,IMMUNOL ABT,W-3000 HANNOVER 61,GERMANY

[2] HANNOVER MED SCH,RHEUMATOL ABT,W-3000 HANNOVER 61,GERMANY

来源：

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY | 1993年 / 22卷 / 06期

关键词：

SULFASALAZINE; DSDNA ANTIBODIES; RHEUMATOID ARTHRITIS; INFLAMMATORY RHEUMATOID DISEASES; DRUG INDUCED LUPUS ERYTHEMATOSUS;

D O I：

10.3109/03009749309095143

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Twenty-four patients with chronic inflammatory joint diseases developed double stranded DNA (dsDNA) antibodies during sulfasalazine (SAS) therapy and 20 of these 24 patients could be followed over a mean period of 11 months. Only one of the patients showed clinical symptoms of systemic lupus erythematosus (SLE). DsDNA antibodies were transient in two thirds of the patients discontinuing SAS treatment and in the same proportion of the individuals who did not interrupt this medication.

引用

页码：299 / 301

页数：3

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