CHROMOSOME ANOMALIES OF MEGALOBLASTIC ANAEMIAS

被引：10

作者：

BOTTURA, C

COUTINHO, V

机构：

[1] Department of Clinical Medicine, Medical School of Ribeirao Prêto

来源：

BLUT | 1968年 / 16卷 / 04期

关键词：

D O I：

10.1007/BF01631668

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Chromosome studies carried out on bone-marrow cells in a case of classical pernicious anaemia in relapse disclosed structural abnormalities in 38% of the metaphases analysed. They were promptly corrected after vitamin B12 administration. No quantitative anomalies were detected. On the basis of these findings the nature of the megaloblastosis and the possible role played by folic acid and vitamin B12 deficiencies in malignant transformation are discussed. © 1968 J. F. Lehmanns Verlag.

引用

页码：193 / &

共 21 条

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[2]

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[3]

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[4]

BETHELL F. H., 1954, ANN NEW YORK ACAD SCI, V60, P436

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