Ligaturing the heads of Galleria mellonella larvae did not lead to a significant change in the heat-fixed total haemocyte counts within a period of at least 7 days. When the thoraces of larvae were ligatured, there was a rapid and striking decrease in unfixed and heat-fixed total haemocyte counts posterior to the ligature. When the larvae were ligatured in the middle of their bodies, the front halves contained significantly more haemocytes than the posterior halves. While there are significantly more circulating haemocytes in mitotic division in the front than in the rear halves, correlations could not be made between estimated frequency of mitoses and specific changes in the total counts in either half. © 1969.