THE EFFECT OF ANTIFOAM AGENTS ON MASS-TRANSFER IN BIOREACTORS

被引:58
作者
KAWASE, Y
MOOYOUNG, M
机构
[1] Center for Biotechnology Research Department of Mechanical Systems Engineering, Kanazawa Institute of Technology, Ishikawa, 921, Nonoichi
[2] Biochemical Engineering Group Department of Chemical Engineering, University of Waterloo, Waterloo, N2L 3G1, Ontario
来源
BIOPROCESS ENGINEERING | 1990年 / 5卷 / 04期
关键词
D O I
10.1007/BF00369581
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
The influence of antifoam agents on the liquid-phase mass transfer coefficient in stirred tank and bubble column bioreactors is studied. A physical model based on a surface-renewal concept and additional data in 40-dm3 bubble column bioreactor are presented. Comparisons between the physical model and the data indicate that the model predicts the maximum influence of antifoam agents on the liquid-phase mass transfer coefficient. © 1990 Springer-Verlag.
引用
收藏
页码:169 / 173
页数:5
相关论文
共 14 条
[1]  
Lee Y.H., Luk S., Aeration, Ann. Reports Ferment. Proc., 6, pp. 101-147, (1983)
[2]  
Yagi H., Yoshida F., Oxygen absorption in fermentors-effects of surfactants, antifoaming agents, and sterilized cells, J. Ferment. Technol., 52, pp. 905-916, (1974)
[3]  
Moo-Young M., Blanch H.W., Design of biochemical reactors, mass transfer criteria for simple and complex systems, Adv. Biochem. Eng., 19, pp. 1-69, (1981)
[4]  
Benedek A., Heideger W.J., Effect of additives on mass transfer in turbine aeration, Biotechnology and Bioengineering, 13, pp. 663-684, (1971)
[5]  
Schugerl K., Lucke J., Lehmann J., Wagner F., Application of tower bioreactors in cell mass production, Adv. Biochem. Eng., 8, pp. 63-131, (1978)
[6]  
Koide K., Yamazoe S., Harada S., Effects of surface-active substances on gas holdup and gas-liquid mass transfer in bubble column, J. Chem. Eng. Japan, 18, pp. 287-292, (1985)
[7]  
Kawase Y., Moo-Young M., Influence of antifoam agents on gas hold-up and mass transfer in bubble columns with non-Newtonian fluids, Appl. Microbiol. Biotechnol., 27, pp. 159-167, (1987)
[8]  
Andre G., Moo-Young M., Robinson C.W., Improved method for the dynamic measured of mass transfer coefficient for application of solid-substrate fermentation, Biotechnology and Bioengineering, 23, pp. 1611-1622, (1981)
[9]  
Akita K., Yoshida F., Bubble size, interfacial area, and liquid phase mass transfer coefficients in bubble columns, Ind. Eng. Chem. Proc. Des. Dev., 13, pp. 84-88, (1974)
[10]  
Walter J.F., Blanch H. W, Bubble break-up in gas-liquid bioreactors, break-up in turbulent flows, Chem. Eng. J., 32, pp. B7-B17, (1986)