IMMUNOCYTOCHEMICAL EVIDENCE OF VERTEBRATE BIOACTIVE PEPTIDE-LIKE MOLECULES IN THE IMMUNE CELL-TYPES OF THE FRESH-WATER SNAIL PLANORBARIUS-CORNEUS (L) (GASTROPODA, PULMONATA)

被引：36

作者：

OTTAVIANI, E ^{[1
]}

COSSARIZZA, A ^{[1
]}

机构：

[1] UNIV MODENA,INST GEN PATHOL,I-41100 MODENA,ITALY

来源：

FEBS LETTERS | 1990年 / 267卷 / 02期

关键词：

Bioactive peptide; Hemocyte; Immunocytochemistry; Planorbarius corneus;

D O I：

10.1016/0014-5793(90)80937-E

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

An immunocytochemical investigation was carried out on round and spreading hemocytes of Planorbarius comeus by using 20 antisera to vertebrate bioactive peptides. The immunotests showed the presence of α1antichymotrypsin-bombesin-, calcitonin-, CCK-8 (INC)-, CCK-39-, gastrin-, glucagon-, Met-enkephalin-, neurotensin-, oxytocin-, somatostatin-, substance P-, VIP-, and vasopressin-immunoreactive molecules in the spreading hemocytes. The round hemocytes were only positive to anti-bombesin, anticalcitonin, anti-CCK-8 (INC), anti-CCK-39, anti-neurotensin, anti-oxytocin, anti-substance P and anti-vasopressin antibodies. No immunostaining was observed with anti-CCK-8 (Peninsula), anti-insulin, anti-prolactin, anti-thyroglobulin and anti-thyroxin (T4) antibodies. As probably in vertebrates, these bioactive peptides may modulate immuno cell function. © 1990.

引用

页码：250 / 252

页数：3

共 29 条

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