A RANDOM EFFECTS MODEL FOR ORDINAL RESPONSES FROM A CROSSOVER TRIAL

被引：54

作者：

EZZET, F

WHITEHEAD, J

机构：

[1] Medical Department, Ciba-Geigy AG, Basel

[2] Department of Applied Statistics, University of Reading, Reading

来源：

STATISTICS IN MEDICINE | 1991年 / 10卷 / 06期

关键词：

D O I：

10.1002/sim.4780100611

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Crossover studies have been successfully conducted in the case of continuous responses. Existing procedures of analysis for ordinal responses, on the other hand, are rarely satisfactory unless strict, usually unrealistic, assumptions are made. In this paper we investigate a random effects model and show that the model is simple and general. Interpretation of parameters is easy, though with a complicated fitting procedure.

引用

页码：901 / 907

页数：7

共 12 条

[1] Hills M., Armitage P., The two‐period crossover clinical trial, British Journal of Clinical Pharmacology, 8, pp. 7-22, (1979)
[2] Scheffe H., The Analysis of Variance, (1959)
[3] Searle S.R., Linear Models, (1971)
[4] Im S., Gianola D., Mixed models for binomial data with an application to lamb mortality, Applied Statistics, 37, pp. 196-204, (1988)
[5] Anderson D.A., Aitken M., Variance component models with binary response: interviewer variability, Journal of the Royal Statistical Society, Series B, 47, pp. 203-210, (1985)
[6] Jansen J., On the statistical analysis of ordinal data when extravariation is present, Applied Statistics, 39, pp. 75-84, (1990)
[7] Clayton D., Cuzick J., Multivariate generalisations of the proportional hazards model, Journal of the Royal Statistical Society. Series A (General), 148, pp. 82-117, (1985)
[8] McCullagh P., Regression models for ordinal data (with discussion), Journal of the Royal Statistical Society, Series B, 42, pp. 109-142, (1980)
[9] Cox M.A.A., Plackett R.L., Matched pairs in factorial experiments with binary data, Biometrical Journal, 22, pp. 697-702, (1980)
[10] Crowder M.J., Beta‐binomial anova for proportions, Applied Statistics, 27, pp. 34-37, (1978)

← 1 2 →