SYNTHESIS, SPECTROSCOPIC CHARACTERIZATION AND INVITRO ANTITUMOR-ACTIVITY OF DI-NORMAL-BUTYLTIN AND DIETHYLTIN TRIMETHOXYBENZOATES - X-RAY STRUCTURE-ANALYSIS OF BIS[DI-NORMAL-BUTYL(3,4,5-TRIMETHOXYBENZOATO)TIN] OXIDE

Di-n-butyltin(IV) and diethyltin(IV) 2,3,4-, 2,4,5- and 3,4,5-trimethoxybenzoates [(CH3O)3C6H2COO]2SnR [Type a] and {[CH3O)3C6H2COO]R2Sn}2O [Type b] have been synthesized and characterized spectroscopically. The crystal structure of bis[di-n-butyl(3,4,5-trimethoxybenzoato)tin] oxide has been determined. The triclinic unit cell contains one centrosymmetric dimer; a = 15.919(2) angstrom, b = 11.711(3) angstrom, c = 13.475(1) angstrom, and alpha = 63.63(2)-degrees, beta = 67.49(1)-degrees, gamma = 76.61(2)-degrees. The geometry of the dimer is very similar to that of bis[di-n-butyl(5-methoxysalicylatotin] oxide, with two different types of five-coordinate tin atoms and one central planar Sn2O2 ring.