INTRASTROMAL CRYSTALLINE DEPOSITS FOLLOWING HYDROGEL KERATOPHAKIA IN MONKEYS

被引:24
作者
PARKS, RA [1 ]
MCCAREY, BE [1 ]
KNIGHT, PM [1 ]
STORIE, BR [1 ]
机构
[1] EMORY UNIV,SCH MED,DEPT OPHTHALMOL,ATLANTA,GA 30322
关键词
CRYSTALS; HYDROGEL; INTRACORNEAL LENS; KERATOPHAKIA; REFRACTIVE SURGERY;
D O I
10.1097/00003226-199301000-00006
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Intrastromal corneal crystals developed in 11 of 49 monkey eyes with hydrogel intracorneal lenticules followed over a 4 year period. All of the eyes, except one, underwent synthetic keratophakia via a microkeratome incision. The diagnosis of crystal formation was initially made by slit-lamp examination and confirmed with specular microscopy (from 21 to 150 days post-hydrogel keratophakia). The crystals were noted to lie in a plane adjacent to the hydrogel lenticule and specular microscopy revealed polychromatic, hyperrefringent crystals with either a rectangular or linear morphology. Prior to intrastromal crystal formation, these corneas developed early postoperative stromal edema (<3 weeks). We hypothesize that early stromal edema in combination with the hydrogel intracorneal lenticule induced the production of lipid crystals by stromal keratocytes.
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页码:29 / 34
页数:6
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