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ASSIGNMENT OF THE 36.5-KDA (RFC5), 37-KDA (RFC4), 38-KDA (RFC3), AND 40-KDA (RFC2) SUBUNIT GENES OF HUMAN REPLICATION FACTOR-C TO CHROMOSOME BAND-12Q24.2-Q24.3, BAND-3Q27, BAND-13Q12.3-Q13, AND BAND-7Q11.23

被引：42
作者：
OKUMURA, K
NOGAMI, M
TAGUCHI, H
DEAN, FB
CHEN, M
PAN, ZQ
HURWITZ, J
SHIRATORI, A
MURAKAMI, Y
OZAWA, K
EKI, T
机构：
[1] INST PHYS & CHEM RES,TSUKUBA LIFE SCI CTR,DIV HUMAN GENOME RES,TSUKUBA,IBARAKI 305,JAPAN
[2] INST PHYS & CHEM RES,TSUKUBA LIFE SCI CTR,GENE BANK,TSUKUBA,IBARAKI 305,JAPAN
[3] MIE UNIV,FAC BIORESOURCES,TSU,MIE 514,JAPAN
[4] MEM SLOAN KETTERING CANC CTR,GRAD PROGRAM MOLEC BIOL,NEW YORK,NY 10021
来源：
GENOMICS | 1995年 / 25卷 / 01期
基金：
日本科学技术振兴机构;
关键词：
D O I：
10.1016/0888-7543(95)80135-9
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Replication factor C is a multimeric primer-recognition protein consisting of five subunits (p145, p40, p38, p37, and p36.5) and is essential for the processive elongation of DNA chains catalyzed by DNA polymerase delta or epsilon in human cells. We have mapped the locations on human chromosomes of the genes coding for the four smaller subunits [p36.5 (RFC5), p37 (RFC4), p38 (RFC3), and p40 (RFC2)] using both PCR amplification from DNAs of a panel of somatic hybrids and fluorescence in situ hybridization to bands 12q24.2-q24.3, 3q27, 13q12.3-q13, and 7q11.23, respectively. (C) 1995 Academic Press, Inc.
引用
收藏
页码：274 / 278
页数：5
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