EFFICIENCY OF ETHIDIUM-BROMIDE MUTAGENESIS AS A FUNCTION OF DIFFERENT STAGES IN THE CELL-CYCLE OF SACCHAROMYCES-CEREVISIAE

被引：5

作者：

COTTRELL, SF

机构：

[1] Department of Biology, Brooklyn College, the City University of New York, Brooklyn

来源：

EXPERIMENTAL CELL RESEARCH | 1979年 / 118卷 / 02期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0014-4827(79)90165-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Periodic increases in sensitivity to ethidium bromide (EB) mutagenesis were observed at specific intervals during successive synchronous cell cycles in the yeast, Saccharomyces cerevisiae. Maximal rates of petite induction roughly coincided with the time of nuclear DNA replication although prolonged treatment with EB ultimately resulted in complete petite induction at all stages during the cell cycle. © 1979.

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页码：398 / 401

页数：4

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