EFFICIENT PROCEDURE TO 4-CARBETHOXY-3-TRIFLUOROMETHYLCYCLOHEX-2-ENONE AND 4-ALKYLATED DERIVATIVES

被引：14

作者：

BEGUE, JP

BONNETDELPON, D

DOGBEAVOU, A

机构：

[1] CNRS-CERCOA, 94320, Thiais

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 04期

关键词：

D O I：

10.1080/00397919208019256

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 4-carbethoxy-3-trifluoromethylcyclohex-2-enone 1a was prepared in one-pot procedure in 90 % yield, from ethyl trifluoroacetoacetate (ETFAAE) and methylvinyl ketone. This reaction has been extended to alkylated ethyl trifluoroacetoacetate.

引用

页码：573 / 579

页数：7

共 7 条

[1] GENERAL-METHOD FOR SYNTHESIS OF TRIFLUOROMETHYLKETONES .2. INDIRECT ALKYLATION OF ETHYL TRIFLUOROACETYLACETATE (ETFAA) [J].

AUBERT, C ;

BEGUE, JP ;

CHARPENTIERMORIZE, M ;

NEE, G ;

LANGLOIS, B .

JOURNAL OF FLUORINE CHEMISTRY, 1989, 44 (03) :377-394

[2] GENERAL-METHOD FOR SYNTHESIS OF TRIFLUOROMETHYLKETONES .1. DIRECT ALKYLATION OF ETHYL TRIFLUOROACETYLACETATE [J].

AUBERT, C ;

BEGUE, JP ;

CHARPENTIERMORIZE, M ;

NEE, G ;

LANGLOIS, B .

JOURNAL OF FLUORINE CHEMISTRY, 1989, 44 (03) :361-376

[3]

BEGUE JP, IN PRESS J CHEM SO 1

[4]

KREISER W, 1981, TETRAHEDRON LETT, P429

[5] NEW GEOMETRIC ISOMERS OF VITAMIN-A .13. FLUORINATED RETINOIDS VIA CROSSED ALDOL CONDENSATION OF 1,1,1-TRIFLUOROACETONE [J].

MEAD, D ;

LOH, R ;

ASATO, AE ;

LIU, RSH .

TETRAHEDRON LETTERS, 1985, 26 (24) :2873-2876

[6]

OSTASZYNSKI A, 1960, B ACAD POLON SCI SC, V8, P619

[7] PREPARATION OF THE 4-CARBOETHOXY-3-TRIFLUOROMETHYLCYCLOHEX-2-ENONE [J].

TORDEUX, M ;

WAKSELMAN, C .

SYNTHETIC COMMUNICATIONS, 1991, 21 (10-11) :1243-1245

← 1 →