THE EFFECTOR INTERACTIONS OF P21(RAS)

被引：211

作者：

MARSHALL, MS ^{[1
]}

机构：

[1] WALTHER ONCOL CTR, INDIANAPOLIS, IN 46202 USA

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1993年 / 18卷 / 07期

关键词：

D O I：

10.1016/0968-0004(93)90175-M

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Genetic, physical and biochemical methods have been used successfully to identify discrete regions of the p21ras protein involved in protein-protein interactions. Of special interest are the effector residues of p21ras, which are essential for downstream signalling. This review details current understanding of what these residues are and how they bind and activate proteins essential to the ras pathway.

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页码：250 / 254

页数：5

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