CATALYSIS BY ZYMOGENS - INCREASED REACTIVITY AT HIGH IONIC-STRENGTH

被引：6

作者：

LONDSDALEECCLES, JD ^{[1
]}

KERR, MA ^{[1
]}

WALSH, KA ^{[1
]}

NEURATH, H ^{[1
]}

机构：

[1] UNIV WASHINGTON,DEPT BIOCHEM,SEATTLE,WA 98195

来源：

FEBS LETTERS | 1979年 / 100卷 / 01期

基金：

英国惠康基金; 美国国家卫生研究院;

关键词：

D O I：

10.1016/0014-5793(79)81154-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

[No abstract available]

引用

页码：157 / 160

页数：4

共 17 条

[1] INDUCTION OF BOVINE TRYPSINOGEN-TRYPSIN TRANSITION BY PEPTIDES SEQUENTIALLY SIMILAR TO N-TERMINUS OF TRYPSIN [J].

BODE, W ;

HUBER, R .

FEBS LETTERS, 1976, 68 (02) :231-236

[2] CRYSTAL-STRUCTURE ANALYSIS AND REFINEMENT OF 2 VARIANTS OF TRIGONAL TRYPSINOGEN - TRIGONAL TRYPSIN AND PEG (POLYETHYLENE-GLYCOL) TRYPSINOGEN AND THEIR COMPARISON WITH ORTHORHOMBIC TRYPSIN AND TRIGONAL TRYPSINOGEN [J].

BODE, W ;

HUBER, R .

FEBS LETTERS, 1978, 90 (02) :265-269

[3] TRANSITION OF BOVINE TRYPSINOGEN TO A TRYPSIN-LIKE STATE UPON STRONG LIGAND-BINDING - REFINED CRYSTAL-STRUCTURES OF BOVINE TRYPSINOGEN-PANCREATIC TRYPSIN-INHIBITOR COMPLEX AND OF ITS TERNARY COMPLEX WITH ILE-VAL AT 1.9 A RESOLUTION [J].

BODE, W ;

SCHWAGER, P ;

HUBER, R .

JOURNAL OF MOLECULAR BIOLOGY, 1978, 118 (01) :99-112

[4] EFFECTS OF IONIC-STRENGTH ON CIRCULAR-DICHROISM SPECTRUM OF CHYMOTRYPSIN [J].

DORRINGTON, KJ ;

HOFMANN, T .

CANADIAN JOURNAL OF BIOCHEMISTRY, 1973, 51 (07) :1059-1065

[5] CRYSTAL-STRUCTURE OF BOVINE TRYPSINOGEN AT 1.8 A RESOLUTION .2. CRYSTALLOGRAPHIC REFINEMENT, REFINED CRYSTAL-STRUCTURE AND COMPARISON WITH BOVINE TRYPSIN [J].

FEHLHAMMER, H ;

BODE, W ;

HUBER, R .

JOURNAL OF MOLECULAR BIOLOGY, 1977, 111 (04) :415-438

[6] CATALYSIS BY CHYMOTRYPSINOGEN - DEMONSTRATION OF AN ACYL-ZYMOGEN INTERMEDIATE [J].

GERTLER, A ;

WALSH, KA ;

NEURATH, H .

BIOCHEMISTRY, 1974, 13 (06) :1302-1310

[7] CATALYSIS BY CHYMOTRYPSINOGEN - INCREASED REACTIVITY DUE TO OXIDATION OF METHIONINE 192 [J].

GERTLER, A ;

WALSH, KA ;

NEURATH, H .

FEBS LETTERS, 1974, 38 (02) :157-160

[8] STRUCTURAL BASIS OF ACTIVATION AND ACTION OF TRYPSIN [J].

HUBER, R ;

BODE, W .

ACCOUNTS OF CHEMICAL RESEARCH, 1978, 11 (03) :114-122

[9]

JENCKS WP, 1969, CHEM ENZYMOLOGY, P376

[10]

KAY J, 1971, J BIOL CHEM, V246, P6661

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