CHEMICAL SYNTHESIS OF PEPTIDE LIBRARIES

被引：72

作者：

SEBESTYEN, F ^{[1
]}

DIBO, G ^{[1
]}

KOVACS, A ^{[1
]}

FURKA, A ^{[1
]}

机构：

[1] EOTVOS LORAND UNIV, DEPT GEN ZOOL, H-1518 BUDAPEST 112, HUNGARY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 03期

关键词：

D O I：

10.1016/S0960-894X(01)80223-7

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

The efficiency of the ''portioning-mixing'' method is demonstrated by the synthesis of more than one million hexapeptides in 5 days. An example is described to illustrate the possibility of completion of partial peptide libraries. Our method is also shown to be suitable to carry out binary peptide synthesis. In addition, a new screening method is outlined based on specific interaction of peptides with living cells.

引用

页码：413 / 418

页数：6

共 17 条

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