NON-GLYCOSIDIC/NON-AMINOALKYL-SUBSTITUTED INDOLOCARBAZOLES AS INHIBITORS OF PROTEIN-KINASE-C

被引：28

作者：

KLEINSCHROTH, J ^{[1
]}

HARTENSTEIN, J ^{[1
]}

RUDOLPH, C ^{[1
]}

SCHACHTELE, C ^{[1
]}

机构：

[1] GODECKE PRECLIN RES, W-7800 FREIBURG, GERMANY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 10期

关键词：

D O I：

10.1016/S0960-894X(01)80995-1

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Non-glycosidic indolocarbazoles lacking aminoalkyl side-chains were synthesized and optimized with respect to potent and selective inhibition of protein kinase C as compared to other serine/threonine and tyrosine-specific protein kinases.

引用

页码：1959 / 1964

页数：6

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