AN EFFICIENT SYNTHESIS OF 2-CHLORO-3-CARBOETHOXY OR 2-CHLORO-3-CYANO 4,5-DISUBSTITUTED AND 5-SUBSTITUTED PYRROLES

被引：15

作者：

FOLEY, LH ^{[1
]}

机构：

[1] UNIV NEW HAMPSHIRE,DEPT CHEM,DURHAM,NH 03824

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 33期

关键词：

D O I：

10.1016/0040-4039(94)88056-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of substituted 2-cyano-4-oxo-alkanoic acid ethyl esters or 2-cyano-4-oxo-alkanonitriles with HCl gas in 2-propanol or concentrated HCl in 2-propanol for the dinitriles provides an efficient synthesis of substituted 2-chloropyrroles from readily available starting materials and reagents.

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页码：5989 / 5992

页数：4

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