Seven days of exercise increase GLUT-4 protein content in human skeletal muscle

被引：67

作者：

Houmard, JA ^{[1
]}

Hickey, MS ^{[1
]}

Tyndall, GL ^{[1
]}

Gavigan, KE ^{[1
]}

Dohm, GL ^{[1
]}

机构：

[1] E CAROLINA UNIV,DEPT BIOCHEM,GREENVILLE,NC 27858

来源：

JOURNAL OF APPLIED PHYSIOLOGY | 1995年 / 79卷 / 06期

关键词：

insulin; glucose transport;

D O I：

10.1152/jappl.1995.79.6.1936

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Insulin-responsive glucose transporter (GLUT-4) content increases by 1.8-fold in skeletal muscle with 14 wk of exercise training [Houmard et al. Am. J. Physiol. 264 (Endocrinol. Metab. 27): E896-E901, 1993]. The purpose of this study was to determine whether more short-term training (7 days) increases GLUT-4 protein content in human skeletal muscle. Seven sedentary men [25.0 +/- 1.1 (SE) yr, 44.1 +/- 2.2 ml . kg(-1). min(-1) maximal O-2 uptake, 14.9 +/- 2.1% body fat] were examined before and after 7 days of cycle ergometer training (1 h/day, 76 +/- 2% maximal heart rate). Needle biopsy samples from the vastus lateralis were used to determine GLUT-4 protein content. Muscle GLUT-4 increased (P < 0.05) by an average of 2.8 +/- 0.5-fold with 7 days of training. GLUT-4 content in skeletal muscle thus increases substantially with short-term exercise training.

引用

页码：1936 / 1938

页数：3

共 24 条

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