POLYMORPHISMS OF OXIDATION AT CARBON CENTERS OF DRUGS AND THEIR CLINICAL SIGNIFICANCE

被引：157

作者：

IDLE, JR

SMITH, RL

机构：

[1] Department of Biochemical and Experimental Pharmacology, St. Mary's Hospital Medical School, London

来源：

DRUG METABOLISM REVIEWS | 1979年 / 9卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.3109/03602537908993896

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

[No abstract available]

引用

页码：301 / 317

页数：17

共 16 条

[1] METABOLISM OF DEBRISOQUINE SULFATE IN RAT, DOG AND MAN [J].

ALLEN, JG ;

BROWN, AN ;

MARTEN, TR .

XENOBIOTICA, 1976, 6 (07) :405-409

[2]

ALLEN JG, 1975, DRUG METAB DISPOS, V3, P332

[3]

ANGELO M, 1975, BRIT J PHARMACOL, V55, pP264

[4] CLINICAL OBSERVATIONS ON EFFECTS OF DEBRISOQUINE SULPHATE IN PATIENTS WITH HIGH BLOOD-PRESSURE [J].

ATHANASSIADIS, D ;

CRANSTON, WI ;

JUELJENS.BE ;

OLIVER, DO .

BMJ-BRITISH MEDICAL JOURNAL, 1966, 2 (5516) :732-+

[5]

BRODIE BB, 1948, J PHARMACOL EXP THER, V94, P29

[6] A KINETIC STUDY OF DRUG ELIMINATION - EXCRETION OF PARACETAMOL AND ITS METABOLITES IN MAN [J].

CUMMINGS, AJ ;

KING, ML ;

MARTIN, BK .

BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1967, 29 (02) :150-&

[7]

DRAYER DE, 1977, CLIN PHARMACOL THER, V22, P251

[8] HYPOTENSIVE RESPONSE TO DEBRISOQUINE AND HYDROXYLATION PHENOTYPE [J].

IDLE, JR ;

MAHGOUB, A ;

LANCASTER, R ;

SMITH, RL .

LIFE SCIENCES, 1978, 22 (11) :979-983

[9]

IDLE JR, BRIT J CLIN PHARMACO

[10] METABOLISM AND EXCRETION OF GUANOXAN IN MAN [J].

JACK, DB ;

STENLAKE, JB ;

TEMPLETON, R .

XENOBIOTICA, 1972, 2 (01) :35-+

← 1 2 →