RELATIONSHIP BETWEEN AGE AND THE CARDIOVASCULAR-RESPONSE TO MEALS

被引：7

作者：

FAGAN, TC

CONRAD, KA

MAYSHAR, PV

MACKIE, MJ

机构：

[1] Departments of Medicine and Pharmacology, University of Arizona College of Medicine, Tucson, AZ

来源：

CARDIOVASCULAR DRUGS AND THERAPY | 1990年 / 4卷 / 02期

关键词：

aging; hypertension; meals; postprandial hypotension;

D O I：

10.1007/BF01857759

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

In 82 healthy normotensive and hypertensive subjects aged 19-79, blood pressure and heart rate were measured for 1 hour before and 2 hours after a meal. Mean blood pressure decreased from 147/93 to 139/83 mmHg supine and from 148/101 to 142/94 mmHg standing (all p<.001). Older subjects had higher premeal blood pressures. There were significant correlations between age and the reductions in supine systolic and diastolic blood pressures and standing systolic blood pressure, i. e., older patients had greater reductions. However, after statistical correction for premeal blood pressure, there was no longer any significant relationship between age and the cardiovascular response to meals. The greater blood pressure reduction after meals in older patients may be due to decreased baroreflex sensitivity in association with higher arterial pressures. The changes in blood pressure due to meals may confound the diagnosis of hypertension and interfere with the interpretation of the response to antihypertensive treatment. © 1990 Kluwer Academic Publishers.

引用

页码：493 / 497

页数：5

共 19 条

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