PRO-DRUGS AS DRUG DELIVERY SYSTEMS .21. PREPARATION, PHYSICOCHEMICAL PROPERTIES AND BIOAVAILABILITY OF A NOVEL WATER-SOLUBLE PRO-DRUG TYPE FOR CARBAMAZEPINE

被引：11

作者：

BUNDGAARD, H

JOHANSEN, M

STELLA, V

CORTESE, M

机构：

[1] UNIV KANSAS,DEPT PHARMACEUT CHEM,LAWRENCE,KS 66045

[2] ROYAL DANISH SCH PHARM,DEPT PHARMACEUT 2,DK-2100 COPENHAGEN O,DENMARK

来源：

INTERNATIONAL JOURNAL OF PHARMACEUTICS | 1982年 / 10卷 / 03期

关键词：

D O I：

10.1016/0378-5173(82)90068-0

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：181 / 192

页数：12

共 18 条

[1] SIMULTANEOUS, RAPID HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC MICROANALYSIS OF PLASMA CARBAMAZEPINE AND ITS 10,11-EPOXIDE METABOLITE - APPLICATIONS TO PHARMACOKINETIC STUDIES IN HUMANS [J].

ASTIER, A ;

MAURY, M .

JOURNAL OF CHROMATOGRAPHY, 1979, 164 (02) :235-240

[2] CLINICAL PHARMACOKINETICS OF CARBAMAZEPINE [J].

BERTILSSON, L .

CLINICAL PHARMACOKINETICS, 1978, 3 (02) :128-143

[3] PRO-DRUGS AS DRUG DELIVERY SYSTEMS .19. BIOREVERSIBLE DERIVATIZATION OF AROMATIC-AMINES BY FORMATION OF N-MANNICH BASES WITH SUCCINIMIDE [J].

BUNDGAARD, H ;

JOHANSEN, M .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1981, 8 (03) :183-192

[4] PRO-DRUGS AS DRUG DELIVERY SYSTEMS .15. BIOREVERSIBLE DERIVATIZATION OF PHENYTOIN, ACETAZOLAMIDE, CHLORZOXAZONE AND VARIOUS OTHER NH-ACIDIC COMPOUNDS BY N-AMINOMETHYLATION TO EFFECT ENHANCED DISSOLUTION RATES [J].

BUNDGAARD, H ;

JOHANSEN, M .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1980, 7 (02) :129-136

[5] HYDROLYSIS OF N-MANNICH BASES AND ITS CONSEQUENCES FOR THE BIOLOGICAL TESTING OF SUCH AGENTS [J].

BUNDGAARD, H ;

JOHANSEN, M .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1981, 9 (01) :7-16

[6]

BUNDGAARD H, 1981, ACTA PHARM SUEC, V18, P129

[7] PRODRUGS AS DRUG DELIVERY SYSTEMS .4. N-MANNICH BASES AS POTENTIAL NOVEL PRODRUGS FOR AMIDES, UREIDES, AMINES, AND OTHER NH-ACIDIC COMPOUNDS [J].

BUNDGAARD, H ;

JOHANSEN, M .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1980, 69 (01) :44-46

[8]

BUNDGAARD H, 1980, ARCH PHARM CHEMI SCI, V8, P29

[9]

FREY HH, 1980, ARCH INT PHARMACOD T, V243, P180

[10] PRO-DRUGS AS DRUG DELIVERY SYSTEMS .13. KINETICS OF DECOMPOSITION OF N-MANNICH BASES OF SALICYLAMIDE AND ASSESSMENT OF THEIR SUITABILITY AS POSSIBLE PRO-DRUGS FOR AMINES [J].

JOHANSEN, M ;

BUNDGAARD, H .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1980, 7 (02) :119-127

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