ASYMMETRIC-SYNTHESIS OF ALPHA-METHYL CARBOXYLIC-ACID DERIVATIVES - STEREOCHEMISTRY IN ACIDIC RING-OPENING OF EPOXIDES

被引：22

作者：

FUKUMASA, M

FURUHASHI, K

UMEZAWA, J

TAKAHASHI, O

HIRAI, T

机构：

[1] NIPPON MIN CO LTD,BIOSCI RES LABS,NIIZO MINAMI,TODA,SAITAMA 335,JAPAN

[2] NIPPON MIN CO LTD,MAT DEV RES LABS,TODA,SAITAMA 335,JAPAN

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 08期

关键词：

D O I：

10.1016/S0040-4039(00)74487-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Optically active alpha-methyl carboxylic acid derivatives were prepared via reaction of microbially produced epoxides with trimethylaluminum. Stereochemistry of the ring opening reaction was discussed through an MO calculation.

引用

页码：1059 / 1062

页数：4

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