SYNTHESIS AND PROPERTIES OF A NOVEL CHIRAL STATIONARY PHASE FOR THE RESOLUTION OF AMINO-ACID ENANTIOMERS

被引：62

作者：

SAEED, T ^{[1
]}

SANDRA, P ^{[1
]}

VERZELE, M ^{[1
]}

机构：

[1] STATE UNIV GHENT,ORGAN CHEM LAB,B-9000 GHENT,BELGIUM

来源：

JOURNAL OF CHROMATOGRAPHY | 1979年 / 186卷 / DEC期

关键词：

D O I：

10.1016/S0021-9673(00)95282-8

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A novel chiral stationary phase hase been synthesized by grafting L-valinetert.-butylamide on to modified polycyanopropylmethyl phenylmethyl silicone (OV-225). This chiral phase can be used for the separation of amino acid enantiomers at temperatures ranging from 60° to 230°. This allows the separation of the protein amino acid enantiomers in one run. The elution properties of six derivatives (O-isopropyl, O-n-butyl, N-trifluoroacetyl, N-pentafluoropropionyl, N-heptafluorobutyryl) on the new chiral phase are compared. © 1979.

引用

页码：611 / 618

页数：8

共 26 条

[1] RESOLUTION OF AMINO-ACIDS ON OPTICALLY-ACTIVE STATIONARY PHASE BY GAS-CHROMATOGRAPHY [J].